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Therefore, any patient who seeks consultation for bothersome symptoms that are attributable to GERD and that persist despite treatment with a PPI merits evaluation and management. Symptoms can include any or all of the following:Dangerous complications also can develop from flu. buy viagra A recent comparison of PPI responders and non-responders found that PPI failure appears to be significantly more common in those with atypical symptoms. One of the most feared complications is a bacterial superinfection. buy viagra The proportion of patients with extraesophageal presentations of GERD that do not respond to medication is less well documented, but the success rate of treating extraesophageal reflux symptoms is lower than that for typical symptoms 139,140,141. A superinfection occurs when the influenza virus attacks a lung and weakens its defenses. buy viagra The reported proportion of patients with heartburn who do not respond to PPIs varies among studies, likely due to differing definitions of failure, dissimilar patient groups, and different medication dosing. This makes the body susceptible to bacterial pneumonia. buy viagra As not all patients who fail to respond to PPIs will have GERD, the most important goal of the diagnostic evaluation in these patients is to differentiate those with persistent reflux as the cause of the ongoing symptoms, from those with non-GERD etiologies. Your doctor will evaluate your symptoms.
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